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Report of Six Surgical Cases

William H. ReMine, MD; Philip W. Brown, Jr., MD; Manuel M. R. Gomes, MD; Edgar G. Harrison, Jr., MD

AMA Arch Surg. 1970;100(3):313-316.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Three cases of tumor of Brunner's glands, diagnosed within a few weeks of each other, prompted review of recent experience with this lesion at the Mayo Clinic. This experience is based on six cases exclusive of two cases reported previously, namely, one by Balfour and Henderson¹ in 1929 and the other by Silverman and colleagues² in 1961.

Brunner's Gland

Wepfer³ in 1679 was the first to mention the presence of duodenal glands, but Brunn (Brunner)⁴ in 1688 first described them in detail.⁵ Embryologically, the glands develop during the sixth month when the cells at the base of the crypts of Lieberkühn extend into the submucosa. In maturity the glands achieve a compound tubular form, arranged in lobules, 0.5 to 1 mm in diameter. They generally are most numerous in the first portion of the duodenum, gradually decreasing in number distally. However, the number and distribution . . . [Full Text PDF of this Article]

Author Affiliations
Rochester, Minn

From the sections of surgery (Dr. ReMine), medicine (Dr. Brown), and surgical pathology (Dr. Harrison), Mayo Clinic and Foundation, and the Mayo Graduate School of Medicine (University of Minnesota) (Dr. Gomes), Rochester, Minn.

Footnotes
Accepted for publication Oct 18, 1969.

Reprint requests to Mayo Clinic, Rochester, Minn 55901.

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