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Intravenous Hyperosmolar Alimentation
William J. Rea, MD;
Walter J. Wyrick, Jr., MD;
Robert N. McClelland, MD;
Watts R. Webb, MD
AMA Arch Surg. 1970;100(4):393-398.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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The value of nutrition in surgery has been well appreciated for the past two decades. Although it has become increasingly obvious that protein metabolism often plays a decisive role in the final outcome of patients who have undergone surgery, it has rarely been possible to obtain a state of positive nitrogen balance following major surgical procedures. Since many investigators have shown that it takes approximately 150 nonprotein calories to spare 1 gm of nitrogen, it was thought impossible to obtain positive nitrogen balance by parenteral routes because of the hypertonic solution required. Recently, Dudrick et al1-3 raised six Beagle puppies to full growth, utilizing only intravenous alimentation. High doses of carbohydrate and protein hydrolysate were infused to supply adequate calories and protein factors. Subsequently, Dudrick et al have supported many patients having serious chronic gastrointestinal disease with intravenous alimentation and have established a positive nitrogen balance in each.4-7
. . . [Full Text PDF of this Article]
Author Affiliations
Dallas
From the departments of surgery of the University of Texas Southwestern Medical School (Drs. McClelland and Webb), The Veterans Administration Hospital (Dr. Wyrick), and Parkland Memorial Hospital (Dr. Rea), Dallas.
Footnotes
Accepted for publication Dec 10, 1969.
Read before the 77th annual meeting of the Western Surgical Association, Dallas, Nov 21, 1969.
Reprint requests to Veterans Administration Hospital, 4500 S Lancaster Rd, Dallas 75216 (Dr. Rea).
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