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George E. Wettach, MD

Arch Surg. 1975;110(10):1252.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Clindamycin has become a popular antibiotic choice following a number of surgical procedures. Clindamycin is a semi-synthetic, wide-spectrum antibiotic derived from the parent compound, lincomycin, and was introduced because it had far fewer gastrointestinal side-effects than lincomycin.

A number of verified hospitalized cases of pseudomembranous colitis associated with oral clindamycin administration have been noted in the literature.^1,2 Pseudomembranous colitis can be a very severe disorder associated with prolonged disabling diarrhea, abdominal pain and cramps, fever, and occasional hematochezia. Friable, edematous mucosa with unusual yellow-white plaques can be seen on sigmoidoscopic examination.

REPORT OF A CASE

Recently we admitted a 40-year-old nurse to the medical service who had undergone an elective cosmetic rhinoplasty and was post-operatively placed on a regimen of 150 mg clindamycin administered orally four times a day to prevent any potential infection from a nasal pack. During the immediate postoperative period the patient developed a very vague . . . [Full Text PDF of this Article]

Author Affiliations
From the Emergency Admitting Department, St. Louis City Hospital, St. Louis.

Footnotes
Accepted for publication Feb 13, 1975.

Reprint requests to Emergency Admitting Department, St. Louis City Hospital, 1515 Lafayette Ave, St. Louis, MO 63104 (Dr. Wettach).

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