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STEVEN WOLINSKY, MD; DAVID N. SILVERS, MD
New York

Arch Surg. 1983;118(8):992.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—In their recent article on thin melanomas invasive to less than 0.76 mm (ARCHIVES 1983; 118:41-44), Paladugu and Yonemoto emphasized that the presence of histologic regression was a poor prognostic sign. In their series, five (45.5%) of 11 thin melanomas with regressive features metastasized. On the other hand, three (12%) of 25 thin melanomas without evidence of regression did so.

Paladugu and Yonemoto concentrated on the importance of regression as a prognostic indicator while failing to address the significance of the 12% (3/25) incidence of metastasis for melanomas that did not exhibit regression. Gromet et al¹ found that two (2%) of 98 such melanomas metastasized within six years. Day et al,² in the prospective New York University—Massachusetts General Hospital (Boston) study on melanoma, reported an eight-year survival rate of 99% for all patients with melanoma invasive to a depth of less than 0.85 mm. The . . . [Full Text PDF of this Article]

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