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C. James Carrico, MD; Jonathan L. Meakins, MD, DSc, FRCSC, FACS; J. C. Marshall, MD, FRCSC; Donald Fry, MD; Ronald V. Maier, MD

Arch Surg. 1986;121(2):196-208.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

INCIDENCE AND PROBLEMS OF MULTIPLE-ORGAN-FAILURE SYNDROMES

The panelists for the discussion were C. James Carrico, MD, from Seattle; Jonathan Meakins, MD, DSc, FRCSC, FACS, from Montreal; Donald Fry, MD, from Cleveland; and Ronald V. Maier, MD, from Seattle.

DR CARRICO: Multiple-organ-failure (MOF) syndrome is a process that occurs following 7% to 22% of emergency operations and between 30% and 50% of operations for intra-abdominal sepsis; MOF syndrome carries a mortality that varies from 30% to 100% depending on the number of organs involved. Treatment usually involves support of the organ (system) function and control of sepsis.^1,2 In developing a clinical description, we can use a classic description of respiratory failure from the late 1960s as a model. Rather than a single organ we need to describe the function of several systems and follow the changes through a series of stages, beginning with the patient who has recently experienced one . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Surgery, University of Washington, Seattle (Dr Carrico); the Departments of Surgery (Dr Meakins) and Microbiology (Dr Marshall), McGill University School of Medicine and The Royal Victoria Hospital, Montreal; the Department of Surgery, Case Western Reserve University (Dr Fry) and the Surgical Service, Veterans Administration Medical Center (Dr Fry), Cleveland; and the Department of Surgery, University of Washington, Harborview Medical Center, Seattle (Dr Maier).

Footnotes
Accepted for publication Nov 22, 1985.

Reprint requests to Department of Surgery, RF-25, University of Washington, Seattle, WA 98195 (Dr Carrico).

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