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VI. THE PROBABLE CAUSE FOR THE REDUCTION IN THE BLOOD PRESSURE FOLLOWING MILD TRAUMA TO AN EXTREMITY

ALFRED BLALOCK, M.D.

Arch Surg. 1931;22(4):598-609.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In a recent communication,¹ the results of experiments in which the blood pressure was reduced to a low level in short periods of time were reported. The time which elapsed in these experiments between the initiation of the trauma and the reduction of the pressure to the desired level varied approximately from one to six hours. The difference in weight of the traumatized and nontraumatized extremites in all instances amounted to more than 4 per cent of the body weight. Johnson and Blalock² found that when a normal dog is bled 0.5 per cent of its body weight at one hour intervals, the blood pressure is usually reduced to a very low level after from eight to ten hours. No evidence was found for the action of a histamine-like substance which causes an immediate general loss of fluid from the blood stream. However, these experiments were probably not . . . [Full Text PDF of this Article]

Author Affiliations
NASHVILLE, TENN.

From the Department of Surgery, Vanderbilt University.

Footnotes
In order to coordinate the previous reports with our major problem, this general title has been adopted. The previous communications, (a) Mechanism and Treatment of Experimental Shock: I. Shock Following Hemorrhage, Arch. Surg. 15:762 (Nov.) 1927; (b) Trauma to Central Nervous System: Its Effect on the Cardiac Output and Blood Pressure: An Experimental Study, ibid. 19:725 (Oct.) 1929; (c) Distribution of the Blood in Shock: The Oxygen Content of the Venous Blood from Different Localities in Shock Produced by Hemorrhage, by Histamine and by Trauma, ibid. 20:26 (Jan.) 1930; (d) Experimental Shock: The Cause of the Low Blood Pressure Produced by Muscle Injury in Dogs, ibid. 20:959 (June) 1930, and (e) Trauma to the Intestines: The Importance of the Local Loss of Fluid in the Production of the Low Blood Pressure, ibid. 22:314 (Feb.) 1931, are to be considered as papers I, II, III, IV and V of this series.

Submitted for publication, April 16, 1930.

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