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A. L. WILKIE, M.D.; HENRY DOUBILET, M.D.

Arch Surg. 1933;26(1):110-121.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

For the past number of years the question of the etiology of cholesterosis of the gallbladder has assumed widespread interest.

In a series of 5,000 gallbladders removed at operation, MacCarty,¹ in 1919, found cholesterosis of the gallbladder to be present in 18 per cent of his cases. In 1921, Mayo² found cholesterosis in 39 per cent of 1,254 cases of disease of the gallbladder. Mentzer³ in 1926 published autopsy reports of 612 cases, with an incidence of cholesterosis as high as 38 per cent. In 1929, Illingworth⁴ noted cholesterosis in 21 of 100 consecutive gallbladders removed at operation.

Anywhere from 20 to 50 per cent of these cases of cholesterosis were associated with gallstones, usually composed of pure cholesterol.

Cholesterosis, so named by Mentzer⁵ in 1925, is a pathologic condition of the mucosa of the gallbladder, consisting macroscopically of tiny yellowish granules lying beneath the . . . [Full Text PDF of this Article]

Author Affiliations
MONTREAL, CANADA

From the Department of Surgery, McGill University.

Footnotes
Read at a Meeting of the Halsted Club, at the Royal Victoria Hospital, Montreal, May 22, 1931.

This work was made possible through the generous grant of the Rockefeller Foundation to the Department of Experimental Surgery.

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