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AN INCREASED INTAKE OF CHLORIDE COMBINED WITH A DIET DEFICIENT IN IODINE AS A FACTOR

JAMES S. HIBBARD, M.D.

Arch Surg. 1933;26(4):648-657.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

At the present time endemic goiter is commonly placed in the category of a deficiency disorder, and attention is being focused on iodine as the lacking element. This is a natural tendency because of its apparent therapeutic value. Hellwig¹ opposed this point of view and stated that a positive factor and not a deficiency of iodine is the essential cause. He believes that an increased intake of calcium chloride represents a positive agent, and if combined with a deficiency of iodine hyperplasia of the thyroid will result.

My purpose in this paper is to report an experimental study on thyroid hyperplasia produced in a relatively nonendemic region based on the theory that calcium chloride represents a positive factor.

REVIEW OF THE LITERATURE

Knappenburg,² in 1919, reported negative results in a series of rats fed on water containing but a small amount of iodine. His experiments were conducted in . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Laboratories of Surgery, College of Physicians and Surgeons, Columbia University.

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