
CARCINOMA OF THE LIPCLINICOPATHOLOGIC ANALYSIS OF SEVENTY-SEVEN CASES AND SUGGESTION FOR RATIONAL PLAN OF TREATMENT
OLAN R. HYNDMAN, M.D.
Arch Surg. 1933;27(2):250-266.
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In a recent review of seventy-seven cases of carcinoma of the lip, several interesting facts were revealed and considered worthy of publication.
Epidermoid carcinoma of the lip comprises from 2 to 3 per cent of all cases of cancer and occurs twelve times as frequently on the lower lip as on the upper.1 The factor of regional metastasis transforms the primary lesion from a relatively innocuous and curable one to an incurable one in at least 50 per cent of the cases. Metastasis to regional nodes (submental and submaxillary) is an embolic phenomenon. As a rule, metastasis from a cancer of the lower lip appears first in the submental glands and then in the ipsolateral submaxillary glands. However, in many instances the first metastases appear in the contralateral submaxillary glands. The regional glands of the neck present an almost impassable barrier to further metastasis. Remote metastases occur in only
. . . [Full Text PDF of this Article]
Author Affiliations
IOWA CITY
From the Department of Surgery, College of Medicine, State University of Iowa.
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