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EXPERIMENTS ON ANIMALS

GEORGE HALSEY HUNT, M.D.

Arch Surg. 1933;27(5):960-969.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The purpose of the experiments here described was twofold: first, to determine whether a combination of avertin (tri-bromethanol) and oil-ether, administered by rectum in experiments on animals, would produce anesthesia measurably deeper or more lasting than avertin alone; and second, to determine the relative safety of these drugs when thus used. The work was undertaken in the hope of securing a combination of anesthetic effects which would give a safe anesthesia in man with the comfortable, rapid induction characteristic of avertin and the more sustained, deeper anesthesia induced by ether, making supplementary inhalation anesthesia unnecessary for operations for which marked relaxation is not required.

LITERATURE

The development of tri-bromethanol in Germany and its introduction into this country some years ago have given rise to an extensive literature, originally in German, but more recently in English also. This literature has been well summarized by many American writers, notably by Waters and . . . [Full Text PDF of this Article]

Author Affiliations
RED BANK, N. J.

From the Department of Surgery, College of Physicians and Surgeons, Columbia University. This experimental work was done while the author was a Junior Fellow in Surgery.

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