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FRED W. STEWART, M.D.

Arch Surg. 1933;27(6):979-1064.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The advent of radiation as a therapeutic agent in neoplastic diseases has stimulated an enormous amount of interest in the fundamental nature of the action of radiation on tissues in general and on tumors in particular. The actual intimate mechanism by which radiation produces injury to cells is vague, and its elucidation must await prolonged biophysical analysis. On the other hand, much information is available regarding the various types of cells or tissues which are especially susceptible to injury by radiation, together with certain of the conditions under which they exhibit this susceptibility. The histologic changes following irradiation have been abundantly described. Much of this knowledge has come from the study of the behavior of tumors under radiation, and from these observations on the behavior of tumors have been formulated certain generalizations which have been called laws of radiosensitivity. It must be realized that these laws are expressions of observed . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Pathological Laboratory of the Memorial Hospital.

Footnotes
This paper was prepared at the request of the American Society for the Control of Cancer as one of a series of monographs on subjects of interest and importance to those engaged in the diagnosis and treatment of cancer.

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