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ERNEST E. ARNHEIM, M.D.; LESTER R. TUCHMAN, M.D.

Arch Surg. 1934;29(1):1-15.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Although the literature on avertin (tribromethanol) rectal anesthesia has become voluminous since the production of the chemical compound tribromethanol by Willstätter and Duisberg, in 1923, there are only a few investigations on the effects in normal persons of the drug administered alone, in the dosage used in basal anesthesia. Before we were willing to employ avertin anesthesia on a large scale in hospital practice, we deemed it advisable to investigate the effects of the drug in normal persons. The numerous reports recorded present either experiments on animals or observations on persons with such complicating factors as operation, auxiliary medication and supplementary anesthesia.

METHOD

We studied avertin anesthesia in fifteen normal people with a view to obtaining information on the uncomplicated effects of the drug. We made observations on the following: age, sex, weight, dosage, constitution, pulse, temperature, respiratory rate and amplitude, condition of the reflexes, state of consciousness, presence of . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the surgical service of Dr. Harold Neuhof and from the laboratories of the Mount Sinai Hospital.

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