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FURTHER STUDIES WITH PARTICULAR REFERENCE TO THE EFFECTS OF HEMORRHAGE

ALFRED BLALOCK, M.D.

Arch Surg. 1934;29(5):837-857.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In many of the experiments on shock which I have previously reported, sodium barbital was used as the anesthetic. Parsons and Phemister used ether or sodium barbital or either of these supplemented by morphine in most of their experiments. Similar findings were reported¹ by the two groups of investigators. Sodium barbital in the dosages employed in these experiments produces unconsciousness, an acceleration of the pulse rate, a decline in the pulse pressure, occasionally a drop in the arterial blood pressure, infrequently early death and frequently a moderate amount of capillary congestion and hemorrhage in some of the organs of the body. Most of these changes are produced by any agent which will produce profound anesthesia for a number of hours. It is unfortunate that the experimental production of a great many pathologic conditions has for humane reasons to be accompanied by a complicating factor such as an anesthetic. However, . . . [Full Text PDF of this Article]

Author Affiliations
NASHVILLE, TENN.

From the Department of Surgery of Vanderbilt University.

Footnotes
This study was aided by a grant from the Fluid Research Fund of the Rockefeller Foundation.

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