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THERAPEUTIC USE OF THE CONCENTRATED STREPTOCOCCUS SERUM OF THE NEW YORK STATE DEPARTMENT OF HEALTHIN PATIENTS WITH INFECTIONS OF THE EAR, NOSE AND THROAT
ADELE E. SHEPLAR, M.D.;
MARTHA JANE SPENCE, M.A.;
WARD J. MacNEAL, M.D.
Arch Surg. 1935;30(1):1-13.
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Inflammatory disease of the upper respiratory region is exceedingly common and in a considerable portion of the patients hemolytic streptococci are present on the mucous membrane in abundance and are evidently etiologically related to the disorder. When the infection extends to the middle ear, the mastoid, the bronchi and the adjacent parenchyma of the lung or to the blood stream, one is not infrequently able to detect streptococci in pure culture in these new situations, a circumstance which offers strong evidence implicating the streptococcus as an important inflammatory agent at the original site, where it had been associated with other microbes. The use of streptococcus serum in the treatment of infections of the upper respiratory tract seems to have been somewhat neglected, except when these inflammations have been associated with the clinical manifestations leading to a diagnosis of erysipelas or of scarlet fever. We are inclined to a somewhat different
. . . [Full Text PDF of this Article]
Author Affiliations
NEW YORK
From the Department of Pathology and Bacteriology, New York Post-Graduate Medical School and Hospital, Columbia University.
Footnotes
This work was made possible by a grant from the Josiah Macy Jr. Foundation.
The patients whose records are utilized in this paper were treated in the clinical services of the following physicians: Dr. A. G. De Sanctis, Dr. S. C. Glasgow, Dr. J. E. Hutton and Dr. D. Macpherson.
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