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THE EFFECTS OF EXTRACTS FROM TRAUMATIZED LIMBS ON THE BLOOD PRESSURE

NORMAN W. ROOME, M.D.; HARWELL WILSON, M.D.

Arch Surg. 1935;31(3):361-370.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Of the various theories suggested as to the mechanism of traumatic shock, two have recently received most attention, viz: (1) that of the absorption of metabolic toxins from the traumatized area with secondary generalized vasodilatation and increased permeability of the capillaries, a theory advocated by Cannon,¹ Cannon and Bayliss,² and others, and (2) that of the local loss of blood or plasma, or both, resulting in a serious decrease in the volume of circulating blood, as supported by the work of Blalock,³ Phemister and co-workers,⁴ Freedlander and Lenhart⁵ and others.

Various investigators (Mason and Lemon,⁶ Carlson, Woelfel and Powell,⁷ Popielski⁸ and Bayliss⁹) have shown that extracts of many tissues contain substances which depress the blood pressure, and this fact has been frequently cited¹⁰ in support of the "toxic theory" of traumatic shock. Carlson, Woelfel and Powell,⁷ however, after examining . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Surgery, the University of Chicago.

Footnotes
This study was aided by a grant from the Douglas Smith Foundation for Medical Research of the University of Chicago.

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