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EXPERIMENTAL STAPHYLOCOCCIC SUPPURATIVE ARTHRITIS AND ITS TREATMENT WITH BACTERIOPHAGE
GEORGE ALBERT LAKE INGE, M.D., Sc.D. (Med.);
JAMES WILLIAM TOUMEY, JR., M.D., Sc.D. (Med.)
Arch Surg. 1935;31(4):642-661.
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Since d'Herelle's1 discovery in 1917 of the phenomenon to which he applied the term bacteriophagy an extensive literature on the subject has accumulated, an increasing part of which has been devoted to the therapeutic use of this biologic principle in clinical medicine. Perhaps because of the dramatic nature of the phenomenon in the test tube, perhaps because the imagination is so fired by a principle which was to rid the world of bacterial diseases, there has often been a great deal of overenthusiasm in the claims advanced for the therapeutic effects of bacteriophage. Such overenthusiasm, born for the most part of insufficient observation or loosely controlled experiments, has given rise among many serious clinicians to a skepticism which denies to bacteriophage any place in the realm of therapeutics. The misfortune of this situation is that a valuable biologic principle is denied a trial by the very men whose work
. . . [Full Text PDF of this Article]
Author Affiliations
NEW YORK
Fellow of the New York Orthopaedic Dispensary and Hospital.; From the laboratories of the New York Orthopaedic Hospital and the Bacteriological Research Laboratory of the Department of Surgery of the College of Physicians and Surgeons, Columbia University.
Footnotes
This work was made possible by a generous gift to the research fund of the New York Orthopaedic Dispensary and Hospital by Col. Edward A. Deeds, of New York.
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