This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

ITS USE IN EXPERIMENTAL STIMULATION OF MAMMARY SECRETION AND ITS ASSAY IN CASES OF CYSTIC DISEASE

CHARLES F. GESCHICKTER, M.D.; DEAN LEWIS, M.D.

Arch Surg. 1936;32(4):598-617.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

That there exists a relationship between the anterior lobe of the hypophysis and lactation has been shown by the work of Grüter and Stricker.¹ Investigations which demonstrated the effect of extracts of the anterior lobe of the hypophysis on mammary secretion have been made by Corner,² Nelson and Pfiffner,³ Gardner and Turner⁴ and Riddle, Bates and Dykshorn.⁵ These studies have shown that when the mammary glands of rats, guinea-pigs, rabbits and dogs have been stimulated by the injection of ovarian hormones, injections of extracts of the anterior lobe of the hypophysis may initiate secretory activity.

Purified lactogenic substances have been prepared from the anterior lobe of the hypophysis by Turner⁶ and his co-workers and by Riddle and his co-workers. The use of these extracts and the response of the crop of the pigeon as a method of bio-assay opened new fields for the investigation . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Surgical Pathological Laboratory, Department of Surgery, the Johns Hopkins Hospital and University.

Footnotes
This work was aided by a grant from the Anna Fuller Fund.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?