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WITH SPECIAL CONSIDERATION OF BIOPSY AND PREOPERATIVE IRRADIATION

L. CLARENCE COHN, M.D.

Arch Surg. 1937;34(2):201-229.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Paget concluded from his observation of fifteen patients, each of whom presented a raw, finely granular nipple or an acute diffuse eczema of the nipple followed in one or two years by cancer of the breast, that chronic conditions of the skin of the nipple and areola are often succeeded by carcinoma of the mammary gland. He suggested and carried out excision of the involved area of the nipple and areola, but, as he himself acknowledged, too late.¹ This conclusion of Paget that the primary lesion was on the nipple and areola and that the tumor of the breast was secondary was debated in the surgical literature from 1874 until 1924, a period of forty-eight years. And Kilgore,² as late as 1921, after studying the material in the laboratory of surgical pathology of the Johns Hopkins Hospital, felt that while Paget's disease is usually primary in the nipple, . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

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