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EVIDENCE OF ETIOLOGIC RELATIONSHIP

CHARLES GOODMAN, M.D.

Arch Surg. 1937;35(6):1126-1144.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The history of medicine makes it axiomatic that diseases of unknown etiology have given rise to innumerable measures for their relief. Success in therapy, however, with few exceptions, was attained only on the discovery of the causative factor. In this respect thromboangiitis obliterans is typical. The literature of the last three decades reveals hundreds of therapeutic suggestions which have been tried and which have yielded little success. This may be attributed to the fact that of all the peculiar etiologic agents which have been suggested, none up to the present time has proved to be the real cause of the condition. Among the causes which have been advanced may be mentioned ethnologic predisposition, metabolic disturbances, climatic and balneologic conditions, endocrine disturbances and syphilis. The toxic effects of drugs and chemicals, such as tobacco, alcohol and ergot, have also been suggested as the possible cause of the disease. However, none of . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

Footnotes
Read before the Section of Surgery of the New York Academy of Medicine, March 5, 1937.

The experimental work was aided by grants to the New York University Typhus Research Fund from Crookes Laboratories, New York, Judge J. N. Proskauer, Charles F. Noyes and S. Blumberg, New York.

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