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CHANGES IN BRAIN VOLUME DURING ANESTHESIA: THE EFFECTS OF ANOXIA AND HYPERCAPNIA
J. C. WHITE, M.D.;
M. VERLOT, M.D.;
B. SELVERSTONE, M.D.;
H. K. BEECHER, M.D.
Arch Surg. 1942;44(1):1-21.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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This investigation was instigated by an unfortunate anesthetic complication which occurred in the Neurosurgical Service of the Massachusetts General Hospital in 1938. A young woman who was rapidly losing her vision because of a hypophysial adenoma that compressed the optic chiasm had a complicating severe bronchiectasis. Operation was therefore undertaken with only local infiltration anesthesia. The moment the tumor had been satisfactorily exposed, however, the patient lost her nerve and insisted that she be placed under general anesthesia. In view of the extensive bronchiectasis it was decided that a relatively low concentration of nitrous oxide with oxygen might be given. Since an intratracheal tube had not previously been inserted and it was deemed inadvisable to disturb the patient's position sufficiently to insert one, it appeared wiser not to use ether. With the onset of a minor degree of cyanosis as the gas was administered, the exposed cerebral hemisphere began to
. . . [Full Text PDF of this Article]
Author Affiliations
BOSTON
From the Neurosurgical and Anesthesia Services of the Massachusetts General Hospital, and the Surgical and Anesthesia Laboratories of the Harvard Medical School at the Massachusetts General Hospital.
Footnotes
Dr. Verlot, who participated in the first half of this investigation, was a Fellow of the Belgian-American Educational Foundation from 1937 to 1939.
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