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EXPERIMENTAL RESEARCH WITH RATS

JANET C. HOLDEN, M.D.; GEORGE CRILE, Jr., M.D.

Arch Surg. 1942;44(6):1106-1110.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The literature on the effect of the vitamin B complex on wound healing is confined to observations on surface healing and is summarized by Arey¹ in his article on wound healing. Saitta² found that a deficiency in the vitamin B complex resulted in diminished power of cicatrization in wounds of the skin, the subcutaneous tissue and the muscles. Oral administration of extract of cereals prevented these changes, and direct treatment of the wounds with the vitamin B complex produced normal activation of the cellular repair. Lauber³ emphasized the unreliability of results obtained with the vitamin B complex and attributed this to a lack of standardization of the exact amounts of the vitamin in vitamin B-rich diets. He found no difference in wound healing between control animals and animals fed with yeast. Larcher⁴ found that wounds in pigeons suffering from a deficiency of the vitamin B complex . . . [Full Text PDF of this Article]

Author Affiliations
CLEVELAND

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