This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

REPORT OF TWO CASES WITH INTRACRANIAL METASTASIS

H. HAROLD FRIEDMAN, M.D.

Arch Surg. 1943;46(3):377-385.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Medical literature contains numerous references to so-called "benign metastasizing goiter" and to "metastasizing normal thyroid tissue." Attention was first drawn to this condition by Cohnheim,¹ who reported such a case in 1876. Many reports have since appeared. In 1926 Simpson² reviewed the literature and collected 77 cases. Since that survey 28 additional cases have been reported in the literature.

The ability of tumors to metastasize at a distance has been generally considered a cardinal criterion of malignancy. Nevertheless certain primary benign neoplasms, chiefly those of connective tissue origin, such as lipomas, myxomas and chondromas, are capable of widespread dissemination. Generalization of benign epithelial tumors, on the other hand, rarely if ever occurs.

According to the literature, adenoma of the thyroid gland apparently forms an exception to the rule of nonmetastasization of benign epithelial tumors. Cases of simple adenoma, of hyperplastic goiter and even of normal thyroid tissue with . . . [Full Text PDF of this Article]

Author Affiliations
BROOKLYN

From the Divisions of Neurosurgery and Thyroid Surgery and the Department of Pathology of the Jewish Hospital.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?