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EXPERIMENTAL STUDY

LUCIA J. DUNHAM, M.D.; ALEXANDER BRUNSCHWIG, M.D.

Arch Surg. 1944;48(5):395-405.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

HISTORY AND PURPOSE

As early as 1895 Leube¹ raised the question of subcutaneous injections of fat for nutritional purposes, in connection with administration of repeated injections of camphor oil to patients with cardiac failure. Attempts were made by a number of workers² to study utilization of subcutaneously injected fat, although absorption from the sites of the injections was admittedly relatively slow. Studies on the utilization of emulsions of fats administered by vein to animals were made by Murlin and Riche in 1915,³ Nomura in 1929,^4a Baba in 1931⁵ and Narat in 1937.^6a,b It was reported that by such injections the lives of 2 starving dogs were prolonged^{6a, b} and in rabbits the iodine and saponification numbers of body fats were altered in the direction of those of the infused fats.^4b While it was suggested that the infused fat was deposited in the . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

Fellow, Swift and Company grant.; From the Department of Surgery, University of Chicago.

Footnotes
This work was carried out under a grant from Swift and Company, Chicago.

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