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STUDIES ON MUSCLE ATROPHYA METHOD OF RECORDING POWER IN SITU AND OBSERVATIONS ON EFFECT OF POSITION OF IMMOBILIZATION ON ATROPHY OF DISUSE AND DENERVATION
JOHN EISENHAUER, M.D.;
J. ALBERT KEY, M.D.
Arch Surg. 1945;51(3):154-163.
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This work was undertaken in an attempt to determine two points: (1) the optimum position of fixation of limbs in order to conserve muscle power and (2) the best method of treatment of muscles paralyzed by loss of nerve supply.
In order to accomplish this, it is necessary to determine the power of given muscles in living animals, then to immobilize these muscles in various positions over an arbitrary period and finally to remove the immobilization and determine the power in the muscles at intervals in order to learn the effect of the immobilization and the ability of the muscle to return to normal with use. This having been accomplished, a series of muscles should be denervated, treated in the same manner and subjected to various types of physical therapy.
As it is stated, the problem seems relatively simple, and we entered on the project with confidence. This we did
. . . [Full Text PDF of this Article]
Author Affiliations
ST. LOUIS
From the Department of Surgery, Washington University School of Medicine.
Footnotes
This work was aided by a grant from the National Research Council.
The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Washington University School of Medicine.
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