This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (9)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

H. C. SALTZSTEIN, M.D.; DAVID J. SANDWEISS, M.D.; JOHN M. HAMMER, M.D.; EDWARD J. HILL, M.D.; HENRY J. VANDENBERG, Jr., M.D.

Arch Surg. 1947;55(2):125-129.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THIS study has been conducted to evaluate the effect of orally administered enterogastrone on a series of dogs in which jejunal ulcer had been produced by the Mann-Williamson operation. Previous study of a similar nature by others¹ has shown that enterogastrone exerts a prophylactic, therapeutic and "immunizing" effect on the experimental Mann-Williamson ulcer when administered parenterally and orally. Recently Ivy and associates² reported a beneficial effect from enterogastrone in preventing recurrence of ulcer in the treatment of patients.

Enterogastrone is a hormone prepared from small intestine mucosa and exerts an inhibiting (or chalonic) effect on gastric motility and secretion. First prepared by Kosaka and Lim³ from the mucosa of the small intestine of dogs, it was subsequently prepared in purer form by Gray, Bradley and Ivy⁴ from the mucosa of small intestine of hogs.

METHOD

The routine Mann-Williamson operation, as reported in a separate publication,⁵ . . . [Full Text PDF of this Article]

Author Affiliations
DETROIT

From the Research Division, Harper Hospital.

Footnotes
Presented at the fourth annual meeting of the Central Surgical Association, Chicago, Feb. 22, 1947.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?