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The "Retained Oxycel Sponge Syndrome"

EDWARD S. VANDERHOOF, M.D.; K. ALVIN MERENDINO, M.D.

Arch Surg. 1949;58(2):182-188.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SINCE the early work on oxidized cellulose by Yackel and Kenyon¹ in 1941, repeated experiments have been conducted on laboratory animals in order to evaluate its hemostatic action, absorbability, and the reaction of tissues to it. Putnam² embedded small pieces of oxidized cellulose paper in the abdominal muscles of cats and dogs and demonstrated the complete absorption of the material in most cases. He also implanted pieces of oxidized cellulose gauze in the folds of the omentum in dogs. Examination after eleven days revealed a thickening of the omentum, but microscopic study demonstrated a minimal inflammatory reaction and the complete resolution of the gauze. Uihlein and others³ conducted studies which indicated that a complete dissolution of the oxidized gauze occurred in four and a half days when it was placed in human surgical wounds. Oxidized cellulose was packed into experimentally produced lacerations of dog's liver, kidney and . . . [Full Text PDF of this Article]

Author Affiliations
MINNEAPOLIS

Dr. Vanderhoof is a Fellow in Surgery at Ancker Hospital, Saint Paul, Minn., under the auspices of the Kellogg Foundation Grant of the University of Minnesota.; Dr. Merendino, on Jan. 1, 1949, assumed the duties of Associate Professor of Surgery, University of Washington, Seattle.; From the Department of Surgery, University of Minnesota, Minneapolis, and the Surgical Service of the Ancker Hospital, St. Paul, Minn.

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