This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

JOHN H. OLWIN, M.D.

Arch Surg. 1949;58(5):603-611.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ADVANCE in recent years in the knowledge of the blood coagulation mechanism and methods for its control has been a major stimulus to investigators in the field of thromboembolism. Reports of the reduction of its incidence postoperatively with the prophylactic use of anticoagulants¹ and the lowering of the mortality rates and complications in coronary thrombosis² have been encouraging. Once a thrombosis develops, the favorable effect of anticoagulants would appear to be a prevention of the spread of the lesion and of the formation of loose clots easily dislodged from the parent thrombus. In addition, recent work³ suggests an increase in the arterial blood flow from administration of dicumarol® and, to a less extent, heparin. There is evidence at present to indicate that the newly discovered prothrombin accelerator factor⁴ is increased early in the thrombotic process,⁵ and two groups of workers have found it to be . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Surgery, Presbyterian Hospital of the City of Chicago, affiliated with the College of Medicine of the University of Illinois.

Footnotes
Read at the Fifty-Sixth Annual Meeting of the Western Surgical Association, St. Louis, Dec. 2, 1948.

This work was made possible through grants from Mr. William H. Kidston and the Otho S. A. Sprague Memorial Institute Fund.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?