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JAMES V. OLIVER, M.D.

Arch Surg. 1949;59(2):199-209.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE FAILURE of bilateral supradiaphragmatic vagotomy to protect against the development of ulcer in the Mann-Williamson dog, as recently reported,¹ has been the stimulus for the work herein described. This investigation was conducted to determine (1) the effect of total gastrectomy with diversion of the duodenal secretions into the terminal portion of the ileum on the development of ulcer and (2) to determine the possible existence of another factor besides the role of acid in the formation of ulcer in man.

The role of acid in the production of ulcer appears to be too definite² to be disputed, and it is also well known that vagotomy produces in the dog a definite decrease in the amount of acid and in the total volume of gastric secretion.³ However, the failure of vagotomy to protect against the development of ulcer in the Mann-Williamson dog led my colleagues and me . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Surgery, University of Illinois College of Medicine.

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