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HARRY SHAY, M.D.; S. A. KOMAROV, M.D., Ph.D.; MARGOT GRUENSTEIN

Arch Surg. 1949;59(2):210-226.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

STUDIES concerning the effects of section of the vagi are numerous and date back to the sixteenth century. In 1883, on the basis of his own experiments and from an extensive review of previous literature, Heidenhain¹ emphasized that bilateral vagotomy performed in the neck was inevitably fatal, yet when done below the diaphragm it appeared to be a rather harmless operation. It remained, however, according to Pavlov,² for Krehl³ in Ludwig's laboratory to evaluate properly the effect of double vagotomy on survival time. He clearly established that animals can survive bilateral section of the vagus below the lung root but invariably succumb after such section in the neck. Later experiments on dogs, cats and rabbits⁴ and the more recent ones of Ferguson⁵ on monkeys amply confirmed the results of these investigators. No generally acceptable explanation is, however, as yet available for the fact that this . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From Fels Research Institute, Temple University School of Medicine.

Footnotes
Presented at the Thirty-First Annual Meeting of the American Physiological Society, Chicago, May 1947.

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