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CIRCULATION OF THE BLOOD AND LYMPH IN FROSTBITE AND INFLUENCE OF THERAPEUTIC COLD AND WARMTHAn Experimental Study
LEON ROSENFELD, M.D.;
JOHN L. LANGOHR, M.D.;
CORA R. OWEN, Ph.D.;
OLIVER COPE, M.D.
Arch Surg. 1949;59(5):1045-1055.
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FROSTBITE is a common injury of man transposed from temperate to cold climate, yet little is known of the physiologic disturbances it creates, and the treatment of it is still in the realm of empiricism. The adverse effects of this injury assumed special importance during the recent war, when these studies were undertaken.
The resemblance of frostbite to burns, the experimental observations of Lewis1 and the experience in the early years of World War II in the treatment of immersion foot with cold2 suggested that the disorder of the arterial and lymphatic circulation induced by frostbite might well be similar to that following burns. Accordingly, as a beginning to a better physiologic understanding and more rational therapy, the experimental studies of the circulatory disturbances of trauma due to burns were extended to frostbite, including the possible use of cold and warmth in treatment.
METHODS
Frostbite was produced experimentally
. . . [Full Text PDF of this Article]
Author Affiliations
BOSTON
From the Surgical Research Laboratories of the Harvard Medical School at the Massachusetts General Hospital.
Footnotes
This work was aided by a grant from the Ciba Pharmaceutical Products, Inc., Summit, N. J.
The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Harvard University.
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