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A Report of Three Cases, with Laparotomy in Two

PHILIP CRASTNOPOL, M.D.; CHARLES F. STEWART, M.D.

Arch Surg. 1949;59(5):993-1000.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ONLY a small proportion of Negroes with the sickle cell trait have the active form of the disease.¹ In 1929 Levy² found that of 213 Negroes admitted in succession to the New Rochelle Hospital, 12, or 5.8 per cent, had "sickling." Murphy and Shapiro³ recorded its incidence in the North American Negro as from 7 to 13 per cent, with anywhere from 1 in 7 to 1 in 40 of those affected showing clinical disease and with a total of almost 135,000 diseased in the United States. Wintrobe⁴ expressed the belief that 1 in 40 Negroes in North America and up to 9 per cent in Central and South America are so affected.

Huck⁵ first pointed out that the trait was transmitted by the male and the female as a mendelian dominant characteristic. It occurs in males in a ratio of 3 to 1⁶; usually children and adolescents are affected, though . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Second Surgical Service, Lincoln Hospital.

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