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Failure of "Oversewing" to Lower Incidence in the Rat and the Guinea Pig

JOHN W. THOMAS, M.D.; JONATHAN E. RHOADS, M.D.

Arch Surg. 1950;61(3):565-567.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IT HAS been a common clinical practice to "reperitonealize" areas of injury to the visceral peritoneum in order to prevent the formation of adhesions between such areas and omentum, intestine or other intraabdominal structures. The usual method of doing this for serosal injuries to the bowel is to draw adjacent uninjured serosa together over the area of injury with interrupted sutures of a fine nonabsorbable material, such as 0000 silk, taking delicate bites of tissue with a small round-pointed needle.

Experiments carried out by Chandy in this laboratory have indicated that silk itself commonly becomes encapsulated by omentum and that the usual seromuscular stitch tied in place would, of itself, produce an adhesion in the experimental animal (rat).

EXPERIMENTAL STUDIES

The following experiments were carried out to see if the incidence of adhesions resulting from areas of bowel denuded of serosa was reduced or increased by oversewing.

The animals used . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Harrison Department of Surgical Research, Schools of Medicine, University of Pennsylvania, and the Surgical Clinic of the Hospital of the University of Pennsylvania.

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