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II. Resection of Thoracic Aortic Aneurysm Using a Stored Human Arterial Transplant

HENRY SWAN, M.D.; CLARENCE MAASKE, Ph.D.; MARVIN JOHNSON, M.D.; ROBERT GROVER, B.A.

AMA Arch Surg. 1950;61(4):732-737.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE PROBLEM of bridging a large gap in a major artery has long been one of importance to both the civilian and the military surgeon. Peirce and his co-workers¹ have recently reintroduced interest in the use of stored arterial homografts for this purpose. In their preliminary studies on dogs these workers demonstrated that such homografts, if taken aseptically within the first few hours after death of the donor animal, could be stored in a standard refrigerator when placed in buffered salt solution containing 10 per cent dog serum. When transplanted into a recipient animal after storage up to fifty days, these homografts would function successfully as a conduit of blood for periods longer than a year. A high percentage of successful "takes" could be obtained by careful anastomotic technics. In addition, it was shown by tissue culture methods that "viable" cells persisted in the stored vessels up to forty . . . [Full Text PDF of this Article]

Author Affiliations
DENVER

From the departments of surgery and physiology, and the Cardiovascular-Pulmonary Research Laboratory, University of Colorado School of Medicine.

Footnotes
Read at the Seventh Annual Meeting of the Central Surgical Association, Chicago, Feb. 17, 1950.

This study was supported in part by United States Public Health Service grant H-241 and in part by the Life Insurance Medical Research Fund.

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