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BROMLEY S. FREEMAN, M.D.; THOMAS K. YOUNG, Jr., M.D.

AMA Arch Surg. 1950;61(6):1145-1150.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PREOPERATIVE sterilization of the skin of patient and personnel has been shown to be the weakest link in the chain of sterile technic.¹ This report reviews the results of a clinical trial for one calendar year of a combination of a detergent (pHisoderm®) with a new antiseptic (3 per cent hexachlorophene) for the preoperative sterilization of both the operative field and the hands of the operating personnel.

RATIONALE OF EXPERIMENT

Previous experimental studies have shown that routine use of hexachlorophene (formerly known as G-11) resulted in a rapid, decided and permanent fall in the resident bacteria of the skin² and that the apparent retention of hexachlorophene in the skin resulted in a cumulative bacteriostatic effect on the resident flora.^2b Guild³ showed that pHisoderm,® a detergent cream composed of a sulfonated ether petrolatum, lactic acid and wool fat cholesterols, possessed active emulsifying, sudsing and dispersing properties with . . . [Full Text PDF of this Article]

Author Affiliations
HOUSTON, TEXAS; TEMPLE, TEXAS

Formerly Chief of the Surgical Service, McClosky (Veterans Administration) Hospital, Temple, Texas.

Footnotes
This study was aided by a grant from Winthrop-Stearns, Inc., New York.

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