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STANDARD METHOD FOR THE PRODUCTION OF PULMONARY EDEMA IN THE DOG
GEORGE L. JORDAN, Jr., M.D.;
LIEUTENANT COMMANDER A. Y. DeLANEY, MC
AMA Arch Surg. 1951;63(2):191-202.
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SINCE pulmonary edema was first described by Maloet in 1752,1 there has been a great deal of clinical and experimental investigation into the problem to elucidate the factors which may be involved in the production of the syndrome. Studies have seldom been made during and after the development of severe pulmonary edema.
For such experiments it is necessary to have a rapid, standard method for the production of pulmonary edema in a fairly large animal which will produce edema in a high percentage of the animals subjected to the procedure. The method employed should produce no physiological alteration which is not likely to be found in human beings with pulmonary edema, and it should not involve any procedure which in itself is likely to cause the death of the animal.
A review of the literature reveals that the following methods have been used for the production of pulmonary edema
. . . [Full Text PDF of this Article]
Author Affiliations
ROCHESTER, MINN.; U.S.N.
Footnotes
Supported by a grant from the David Trautman Schwartz Research Fund.
An abridgment of a thesis submitted by Dr. Jordan to the Faculty of the Graduate School of Tulane University in partial fulfillment of the requirements for the degree of Master of Science in Surgery.
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