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PAUL F. WARE, M.D.; CHESTER W. HOWE, M.D.

AMA Arch Surg. 1951;63(2):229-233.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ESOPHAGEAL fistulas in the laboratory animal have been utilized for a variety of experimental purposes. Pavlov and Schumova-Simanovskaia¹ used dogs with cervical and gastric fistulas in their studies on the relationship of the vagus nerves to gastric secretion. Pavlov² states that neck infection in the dog is serious and often fatal. In 1929 Saint and Mann³ cited the appalling mortality associated with experimental surgery of the esophagus and called attention to the factors of poor blood supply and lack of a true serosa. Saint⁴ later stressed the risk of fatal infection of the pleura and the cellular tissues of the neck. Allen⁵ mentions the frequency of mediastinitis during the course of experimental surgery when the lumen of the esophagus is opened. After the clinical experiences of Sturgeon⁶ and Lahey⁷ with esophageal diverticulas, both Allen⁵ and Markowitz⁸ advocated the use of two . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Surgical Service and the Smithwick Foundation of the Massachusetts Memorial Hospitals and the Department of Surgery of the Boston University School of Medicine.

Footnotes
Supported by a grant from the Trustees under the wills of Charles A. King and Marjorie King.

This paper is No. 1 in a series on a combined experimental and clinical approach to the surgical treatment of peptic ulcer.

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