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An Experimental Study

H. J. CORPER, M.D., Ph.D.; MAURICE L. COHN, Ph.D.

AMA Arch Surg. 1951;63(5):652-655.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

AN EARLY axiom in tuberculosis warned against opening or manipulating tuberculous foci. In vitro, the mammalian tubercle bacillus assumes the aspects of a self-limited grower on the surface of solid nutrient mediums as well as on the surface of (and submerged in) liquid mediums.¹ The spread of growth in vitro or in vivo, therefore, to some extent appears to be movement from external sources and not inherent in the bacilli themselves. Many modern procedures to benefit the patient take full cognizance of these facts and yet at times they are overlooked, as in surgical intervention, in which, unfortunately, evaluation is difficult or impossible. Earlier investigations demonstrated the detrimental effect of certain foreign materials² and spreading agents³ on tubercle bacilli and on tuberculosis. With increasing use of surgical procedures, it becomes important to determine the effect of simple traumatism on the spread of tuberculosis, the significance of the . . . [Full Text PDF of this Article]

Author Affiliations
DENVER

From the Research Department, National Jewish Hospital at Denver, and the University of Colorado School of Medicine.

Footnotes
This investigation was aided by a gift from Morton May in memory of Florence G. May.

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