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Experimental Study

ALFRED LARGE, M.D.

AMA Arch Surg. 1952;65(4):522-531.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

DIRECT choledochoduodenostomy is not infrequently performed in patients who require common duct reconstruction, especially in those instances when the distal end of the common duct cannot be found. Although some regurgitation of the duodenal content into the biliary system is bound to occur after such an operation, the effect of this reflux may or may not be important, depending upon the degree of ascending cholangitis that develops. The experiment to be reported in this paper was undertaken in an attempt to determine the incidence and severity of ascending infection following elimination of the sphincter of Oddi from the extrahepatic biliary system.

METHOD

Mongrel dogs were used as experimental animals. At a preliminary operation the common bile duct was doubly ligated and cut across close to the duodenum (Fig. 1). One to three weeks later the abdomen was again opened, and the greatly dilated common bile duct (often the diameter of . . . [Full Text PDF of this Article]

Author Affiliations
DETROIT

From the Department of Surgery, Wayne University College of Medicine, and the Fifth Surgical Service, Grace Hospital.

Footnotes
Read at the Ninth Annual Meeting of the Central Surgical Association, Toronto, Canada, March 7, 1952.

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