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A Comparative Study

WILLIAM G. ANLYAN, M.D.; DERYL HART, M.D.; NICHOLAS G. GEORGIADE, M.D.; MARY A. POSTON, M.A.

AMA Arch Surg. 1954;68(1):28-32.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IT HAS been of interest during the past two years to compare the effectiveness of oxytetracycline (Terramycin) and neomycin in the preoperative preparation of the colon and rectum.

The late Dr. John Lockwood¹ emphasized that in intestinal surgery chemotherapy of any type was secondary in importance to a good anastomosis on a decompressed bowel with a good blood supply. Poth² has shown that there is a much improved quality of healing of large bowel anastomoses performed in dogs after the preoperative use of intestinal antiseptics.

Dearing and Needham³ and others * have reported on the effect of oxytetracycline on the intestinal bacterial flora of patients, with special reference to the preoperative use of oxytetracyline. Poth and his associates have reported on the effectiveness of neomycin alone and of neomycin combined with phthalylsulfathiazole in the intestinal antisepsis of patients prior to operation. These studies were conducted on 51 . . . [Full Text PDF of this Article]

Author Affiliations
DURHAM, N. C.

From the Departments of Surgery and Bacteriology, Duke University School of Medicine.

Footnotes
Terramycin was supplied by Charles Pfizer & Company, Inc., Brooklyn 6.

Neomycin was supplied by Commercial Solvents Corporation, New York 17.

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