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Practical Applications in Segmental Resection of Pulmonary Tissue

BRIAN BLADES, M.D.

AMA Arch Surg. 1954;69(4):525-529.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE ABILITY of an organ to withstand partial or complete ischemia not only is of academic interest but may have practical importance. Techniques of operations in certain regions, tissue transplantations, safe timing in occlusion of blood supply, and other important clinical principles may depend upon the tolerance of the organs to total or complete occlusion of the blood supply.

Interest in transplantation of homologous lung tissue led to our original experiments on the ability of the lungs to withstand interruption of the blood supply.¹ The experiments were designed to determine the length of time the lung would remain viable after total occlusion of its circulation. The results of the original study were astonishing. In dogs, the blood supply of the lungs could be occluded for as long as 360 minutes with the survival of lung tissues. The Table reveals the duration of ischemia and the gross and microscopic changes. . . . [Full Text PDF of this Article]

Author Affiliations
WASHINGTON, D. C.

From the Surgical Research Laboratory, Department of Surgery, The George Washington University School of Medicine. Supported by the Veterans Administration Contract, V1001-M-3210. M-3210.

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