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Measurement by Radioactive Colloid

GEORGE L. NARDI, M.D.

AMA Arch Surg. 1955;70(4):530-534.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Surgical production of splenorenal shunts in the treatment of portal hypertension has stimulated interest in the dynamics of liver blood flow. The objective of such shunts is to eliminate bleeding from esophageal varices, presumbably by reducing portal vein pressure. The reduction in portal vein pressure achieved by such a shunt can be measured by direct manometric reading at the time of surgery. However, such data are of limited value. The measurements can be obtained only at the time of operation; they vary with the systemic blood pressure, and they are frequently not reproducible in closely adjacent areas of the same vein.

It would seem desirable, then, to have some additional measure of hepatic hemodynamics. Bradley and co-workers* have estimated the liver blood flow by sulfobromophthalein (BSP) clearance. They found a reduction in the hepatic blood flow of cirrhotics, which was further reduced after a portacaval shunt.

Dobson and Jones⁴ . . . [Full Text PDF of this Article]

Author Affiliations
Boston

From the Department of Surgery, Harvard Medical School, and the Surgical Services, Massachusetts General Hospital.

Footnotes
The work described in this paper was supported by a grant from the Essex North Chapter of the Massachusetts Heart Association.

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