 |
|
Experimental Meckel's DiverticulumThe Production of Peptic Ulcers by the Internal Drainage of a Heidenhain Pouch
J. L. BRAVO, M.D.;
J. BARCENA, M.D.;
C. M. BAUGH, M.D.;
L. R. DRAGSTEDT, II, M.D.;
C. F. MOUNTAIN, M.D.;
H. RAGINS, M.D.;
E. S. LYON, M.D.;
L. R. DRAGSTEDT, M.D., Ph.D.
AMA Arch Surg. 1957;74(2):255-258.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
It has been shown that ulcers resulting from deviation of duodenal, pancreatic, and biliary secretions are due primarily to the corrosive action of undiluted and unneutralized gastric juice. A clear example of this corrosive effect is observed in those cases of Meckel's diverticulum containing heterotopic gastric mucosa with a peptic ulcer in the ileum adjacent to the entrance of the diverticulum. This corrosive action of gastric juice was demonstrated experimentally by Matthews and Dragstedt * by anastomosing Pavlov pouches to the ileum of dogs. Stoma ulcers occurred in 100% of the cases. A similar result was obtained by Barry and Florey,3 working with cats and pigs. In the experiments of Gage, Ochsner, and Hosoi4 ulcers occurred in only 71% of the animals when the Heidenhain pouches were constructed from the lesser curvature of the stomach. This can be explained by the greater acidity of the gastric juice secreted from
. . . [Full Text PDF of this Article]
Author Affiliations
Chicago
From the Department of Surgery of the University of Chicago.
Footnotes
Submitted for publication Aug. 1, 1956.
This work has been aided by grants from the Otho S. A. Sprague Memorial Institute and from the Division of Research Grants and Fellowships of the National Institutes of Health, United States Public Health Service.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
