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BROCK E. BRUSH, M.D.; MELVIN A. BLOCK, M.D.; THOMAS GEOGHEGAN, M.D.; DWIGHT C. ENSIGN, M.D.; JOHN W. SIGLER, M.D.

AMA Arch Surg. 1957;74(5):675-679.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

The advent of corticotropin (ACTH) and the development of ulcer symptoms in patients on steroid therapy have led to a reevaluation of the peptic ulcer problem. Peptic ulcer previously occurred largely in a certain type of person who was said to have an "ulcer diathesis," but the introduction of new ulcerogenic agents has somewhat changed the picture. It is to be noted that most of these ulcerogenic agents are antiarthritic or antirheumatic compounds, and our material is obtained from patients suffering originally from these chronic ailments. The frequency of peptic ulceration in patients on steroid therapy appears to be more than coincidental. Although a medical ulcer program and discontinuance of the offending agents usually suffice, there are times when complications of the ulcer arise which demand surgical intervention. Our experience with this type of ulcer and its complications forms the basis of this report.

Physiological Considerations

Peptic ulcer has . . . [Full Text PDF of this Article]

Author Affiliations
Detroit

From the Divisions of General Surgery and Arthritis, Henry Ford Hospital.

Footnotes
Read at the 64th Annual Meeting of the Western Surgical Association, Cincinnati, Nov. 29, 1956.

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