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CHARLES B. PITTINGER, M.D.; STUART C. CULLEN, M.D.; DEAN C. WATLAND, M.D.

AMA Arch Surg. 1957;75(3):339-341.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Fluothane (2-b r o m o-2-chloro-1,1,1-trifluoroethane) is a potent, nonexplosive anesthetic agent recently developed by Imperial Chemical Industries of England. It is a volatile liquid having the chemical structure indicated in the Figure. Johnstone¹ published the first clinical report of its use in September, 1956; another, by Bryce-Smith and O'Brien,² appeared in December, 1956. In addition to the properties already mentioned, Fluothane was stated to possess a not unpleasant odor, which, in addition to its great potency, allowed for short, pleasant inductions, usually with little or no excitement. Excellent muscular relaxation, rapid recovery, and a low incidence of nausea and emesis were also reported. Although hypotension accompanied by bradycardia was said to occur, the impression gained from the available information was sufficiently encouraging to prompt an investigation of this new anesthetic agent.

The purpose of this report is to present some clinical observations on the first 220 . . . [Full Text PDF of this Article]

Author Affiliations
Iowa City

From the Division of Anesthesiology, Department of Surgery, State University of Iowa College of Medicine.

Footnotes
Submitted for publication March 4, 1957.

Read at the 14th Annual Meeting of the Central Surgical Association, Chicago, Feb. 21, 1957.

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