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JOSEPH A. BUCKWALTER, M.D.; MICHEL N. JURAYJ, M.D.

AMA Arch Surg. 1957;75(3):352-361.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

An abundance of articles has been published concerning the clinical and pathologic aspects of epidermoid carcinoma of the anorectal canal. An occasional article refers to the possible role of benign anorectal disease in the etiology of this lesion. Cattell and Williams⁷ discussed this possibility but reported a history of antecedent benign disease in only 1 of their 10 cases. Buie and Brust⁶ found a history of local disease in 34 of 51 patients. Bensaude and associates,³ Rosser,^12-14 Keyes,¹¹ Kerr,¹⁰ Gabriel,⁸ Bacon and associates,² and Grodsky⁹ have mentioned the possibility but have not presented convincing evidence to support an association between previous benign disease and epidermoid carcinoma of the anus or rectum.

The more frequent reference to the possibility of such an association in earlier than in later articles suggests that this possibility and its clinical implications are not widely appreciated today. . . . [Full Text PDF of this Article]

Author Affiliations
Iowa City

From the Department of Surgery, State University of Iowa College of Medicine.

Footnotes
Submitted for publication March 4, 1957.

Read at the 14th Annual Meeting of the Central Surgical Association, Chicago, Feb. 21, 1957.

Richard Shropshire, M.D., Washington, D. C., assisted in the collection of the data. Lloyd A. Knowler, Ph.D., Chairman of the Department of Mathematics and Astronomy, State University of Iowa, examined the data for statistical significance.

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