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C. A. HELLWIG, M.D.; J. W. WELCH, M.D.; P. N. WILKINSON, A.B.

AMA Arch Surg. 1958;76(3):331-333.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

More than 100 years ago (1829) Cruveilhier⁴ made the observation that chronic gastric ulcers are usually situated at the lesser curvature. This has been confirmed by many writers, but no valid explanation for this peculiar localization has come forward.

There is strong evidence (Bolton² and Konjetzny⁹) that chronic gastric ulcers arise from acute ulcers. Thus two problems present themselves: first, the cause of acute ulcers, and, second, the factors which lead to the persistence or nonhealing of ulcers. Acute ulcers are found not only at the lesser but also on the greater curvature, and at the cardia as well as in the fundus (Stewart¹⁵). Their etiological factors—chemical, hormonal, neurological, and psychological—have been widely discussed in modern treatises. However, very little attention has been given to the second problem: Why ulcers at the lesser curvature become chronic. The peculiar localization of almost all chronic stomach ulcers at . . . [Full Text PDF of this Article]

Author Affiliations
Halstead, Kan.

Footnotes
Submitted for publication July 24, 1957.

The material on which this paper is based was presented as part of a scientific exhibit of the Section on Pathology and Physiology at the 106th Annual Meeting of the American Medical Association, New York, June 3-7, 1957.

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