 |
|
Effect of Intravenous Nutrient Solutions on Ventricular Fibrillation in the Hypothermic Dog
LEONARD J. CARANNA, M.S.;
FRANCOIS J. P. TELMOSSE, M.D.;
HENRY SWAN, M.D.
AMA Arch Surg. 1958;76(3):394-397.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
Introduction
A high incidence of ventricular fibrillation in dogs during general hypothermia at body temperatures below 28 C (82.4 F) has been reported.1-4 A few pharmacological agents have been evaluated for their effects in reducing the incidence of fibrillation at low temperatures.5,6 It is noteworthy that the agents so far reported were administered after the animal had reached the desired hypothermic level.
Recently, aminoacetic acid (glycine) was shown to be of thermogenic value by its ability to aid in rapid rewarming to normal body temperature.7 Furthermore, a prolongation of cooling time was attributed to the aminoacetic acid administration, which began prior to ice-water immersion. Amino-acetic acid has also been shown to possess an antiarrhythmic effect in cyclopropane-epinephrine-induced ventricular arrhythmias8 and in hypothermia.9 Evidence, therefore, suggests that aminoacetic acid possesses both thermogenic and antiarrhythmic properties.
The present study was performed to test whether these effects were
. . . [Full Text PDF of this Article]
Author Affiliations
Denver
From the Halsted Surgical Experimental Laboratory, University of Colorado School of Medicine.
Footnotes
Submitted for publication Aug. 19, 1957.
This study was aided in part by a grant from the U. S. Public Health Service (H-2710), and in part by a contract with the Surgeon General, U. S. Army (Contract No. DA-49-007-MD-572).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
