 |
|
Effect of Cigarette Smoke Tar on the Hamster Pouch
CONDICT MOORE, M.D.;
A. JAMES MILLER, M.D.
AMA Arch Surg. 1958;76(5):786-793.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
Introduction
Many attempts are being made to investigate the precise role of tobacco in the occurrence of cancer of the human mouth, throat, and lungs. This work has been stimulated by recent experimental studies and epidemiological data,1-4 the latter pointing to some significant etiological association between tobacco and these cancers. Such an association also has been demonstrated between mouth and throat cancer, the excessive consumption of alcohol, and certain states of chronic malnutrition, such as the Plummer-Vinson syndrome.5-7 However, tobacco maintains the most consistent association with mouth cancer, as compared with alcohol and diet. Since cigarettes are by far the most widely used form of tobacco in this country, we became interested in studying the effects of cigarette smoke tar in experimental animals.
Materials and Methods
We have selected as our experimental tissue the oral pouch of the golden hamster (Mesocricetus auratus) because of its proximity to the
. . . [Full Text PDF of this Article]
Author Affiliations
Louisville
From the Departments of Surgery and Pathology, University of Louisville School of Medicine.
Footnotes
Read at the 65th Annual Meeting of the Western Surgical Association, Salt Lake City, Nov. 22, 1957.
Work supported by Grant No. C-2335 from the Grants Division, National Cancer Institute, National Institutes of Health, U. S. Public Health Service, Washington, D. C.
Dr. William Christopherson, Professor of Pathology, made suggestions during the progress of this work, and Mr. John Hagan and Miss Hazel Short gave technical assistance.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
