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Electroencephalographic, Blood Pressure, and Blood Volume Correlations in Dogs During Hemorrhagic Hypotension With and Without Ganglionic Blocking Agents

BYRON M. BLOOR, M.D.; RICHARD D. FLOYD, M.D.; KENNETH D. HALL, M.D.; DAVID H. REYNOLDS, M.D.

AMA Arch Surg. 1958;77(1):65-74.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In recent years the initial wave of enthusiasm for the use of induced hypotension by ganglionic blockade during certain surgical operations has been supplanted by a desire for a more careful appraisal of the technique.^1-3 Clinical analyses of surgical patients subjected to hypotension have provided useful, but incomplete, information because of the many uncontrollable variables—in particular, the loss of blood during surgery. Although much work has been done on the various aspects of hemorrhagic hypotension or shock and the influence thereon of surgical or chemical sympathectomy, most of the interest has been directed toward visceral changes^4,5 and survival rates in animals kept hypotensive by the techniques of Wiggers and Fine.^6-10 Except for a few isolated instances,^11-13 the relationship between the cerebral and the systemic hemodynamics has received very little attention, and little is known about the cerebral hemodynamic responses either to hemorrhagic hypotension, per se, or . . . [Full Text PDF of this Article]

Author Affiliations
Durham, N. C.

Present Address (Dr. Bloor): Cleveland City Hospital, Cleveland 9.; From the Departments of Neurosurgery, General Surgery, and Anesthesiology, Duke University Hospital, and Veterans' Administration Hospital.

Footnotes
Submitted for publication Feb. 6, 1958.

Presented at the meeting of the Harvey Cushing Society, Detroit, April 25, 1957.

This investigation was supported (in part) by research grants (B-784 and H-1811 [C2]) from the National Institute of Neurologic Disease and Blindness and the National Heart Institute, National Institutes of Health, U. S. Public Health Service, and the United Medical Research Foundation of North Carolina.

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