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MORTON D. PAREIRA, M.D.; NELLE SICHER, A.B.; STANLEY LANG, Ph.D.

AMA Arch Surg. 1958;77(2):191-195.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It is known that the organism attempts to sustain hemoglobin and plasma proteins at the expense of tissue proteins.⁵ Furthermore, it is recognized that plasma protein concentration and hematocrit percentage may yield normal values after this mechanism has been exhausted by virtue of simultaneous alterations in the absolute values of some of the blood components. This recognition arises from ubiquitous experience with random, simultaneous determinations of absolute and relative levels of various intravascular components in subjects with nutritional deficits the types and magnitudes of which are not precisely defined. Keys et al.¹ made such observations in one type of nutritional deficit (chronic underfeeding) in human volunteers who were underfed to 76% of their initial body weight. Such studies have not been made in other types of nutritional abnormalities. Furthermore, the study cited above was not pursued into the zone of extreme undernutrition. The latter cannot, of course, be . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

From the Surgical Section of the Research Institute, the Jewish Hospital, and the Department of Surgery, Washington University School of Medicine.

Footnotes
Submitted for publication March 6, 1958.

Aided by a grant from Mead Johnson & Company, Evansville, Ind.

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